BOTOX®, Dysport®, Xeoman® and Myobloc® are therapeutic muscle-relaxing agents that work at motor nerve endings (nerves that lead to muscles).  They are a class of drugs called neurotoxins. When considering neurotoxin therapy, it is important to understand how the product works, the history of its use in patients, its protein content, and possible side effects. This page is designed to help you understand more about these toxins: what they are, how they work, and how they can help you.

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Aproved Medical Uses Uses:
  • Blepharospasm - BOTOX® is indicated for the treatment of blepharospasm associated with dystonia, including benign essential blepharospasm or VII nerve disorders in patients 12 years of age and above.
  • Strabismus  - BOTOX® is indicated for the treatment of strabismus in adults.
  • Cervical Dystonia - In 2000, the FDA approved BOTOX® for the treatment of CD in adults to decrease the severity of abnormal head position and neck pain associated with CD. More recently Dysport, Xeoman and Myobloc have also been approved for this condition. These may be injected under EMG guidance.
  • Hyperhydrosis - (excessive sweating) of the Palms and Arm Pits
  • Upper Limb Spasticity - e.g. after stroke or trauma to the brain or spinal cord.
  • Chronic Migraine on Adults - Headaches recurring more than 14 days per month.
  • Hemifacial Spasm (7th cranial nerve disorders)-Twitching of facial muscles.
  • Migraine Headaches.
  • Oral Mandibular Dystonia-involuntary opening or closing of the jaw.
Accepted Medical Uses
  • TMJ Syndrome
  • Tension and Migraine Headaches-now approved
  • Muscle Spasticity due to Stroke, Multiple Sclerosis, and Trauma
  • Essential Tremor of the Head or Hand
  • Muscular Pain due to Fibromyalgia, and Cervical and Lumbar Sprains/Strains
  • Essential Tremor of the Head or Hand
  • Writer's or Occupational Hand Cramping
  • Excessive Drooling in Parkinson's Disease
  • Spasticity due to stroke or trauma to the brain or spinal cord
  • Oral Mandibular Dystonia ( A condition similar to TMJ Syndrome)
  • Facial Tics including Tourette's Syndrome tics
  • Headaches - Migraine or Muscle Contraction Headaches
  • Writer's Cramp- also known as Task Specific Dystonia
Accepted Cosmetic Uses


  • Blepharospasm

    Blepharospasm is a disorder of the muscles that control eyelid movement. Spasms of the eyelid lead to frequent blinking. Blepharospasm often affects both eyelids, making it difficult to open the eyelids. In severe cases, this debilitating condition can lead to what is known as "functional blindness" because the patient is unable to open or keep open the eyelids for any significant period of time. 
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  • Hemifacial Spasm

  • Cervical Dystonia

    Cervical dystonia (CD), also known as spasmodic torticollis, belongs to a group of disorders known as focal dystonias. Patients with CD have involuntary contractions of the neck and shoulder muscles that cause the head to twist in abnormal positions.1 Neck muscles may also contract repetitively, producing uncontrollable head movements.
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  • Upper Limb Spasticity

  • Cosmetic Uses

    Botulinum toxin (Botox) works by weakening the muscles of facial expression which insert on the under surface of facial skin. Once the resting tone of these muscles are weakened, the pull of the muscles relax and the skin flattens out. This is an entirely different approach to treating the aging face. Collagen and fat injections work by filling in a wrinkle. These fillers are not as effective as Botox in improving the frown wrinkles between the eyebrows. By physiologically weakening the muscles, these wrinkles are removed naturally. 
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  • Primary Axillary Hyperhydrosis

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