Approved Medication:

Below is an abbreviated list of medications used to treat neurological disorders. 

New Seisure Medications:

  • Keppra
    This is a newer antiepileptic for seizure disorders. It can be given orally or intravenously. It is for both generalized and partial onset seizures. It has limited side effects.

  • Vimpat
    This is also a new antiepileptic. It is approved for partial onset seizures.
     
  • Fosphenytoin
    The medication metabolizes quickly to phenytoin but has a lower side effect profile. It also can be given in IV loading doses unlike phenytoin. Administration guidelines will be similar to Dilantin.

  • Fycompa
  • Sabril
  • Gabitrel

Parkinson's Drugs:

  • Sinemet
    This is the primary drug for treating Parkinson's Disease. It contains levodopa/carbadopa.

  • Mirapex
    This is also a Parkinson's drug. It mimics dopamine to manage symptoms.

  • Requip
    This is also a Parkinson's drug. It mimics dopamine to manage symptoms.

  • Azilect
    This is a MAO inhibitor that allows levodopa to accumulate in the brain. It is often given as the initial treatment. Dietary restrictions during its use have been modified.

  • Selegiline (Eldyprel and Zelapar)
    These drugs enhance one's own levodopa brain content. They are used in the early course of Parkinson's.

Peripheral Neuopathies

  • Gabapentin, Lyrica, Cymbalta
    Gabapentin and Lyrica are weak seizure medications that have been found very useful in pain control of peripheral neuropathies and the pain of shingles. Lyrica and Cymbalta an antidepressant have been approved for fibromyalgia as well.

Multiple Sclerosis Drugs:

  • New Oral MS Drugs
    • Gelenya - 1/day
    • Aubagio - 1/day
    • Tecfidera - 2/day
  • New Injectable MS Drugs
    • Pegylated Interferon - BiMonthly
  • Copaxone (Copolymer 1)
    Copolymer 1 shows significant beneficial effect on multiple sclerosis relapse rate and disability in a phase 3 trial for relapsing and remitting multiple sclerosis. A 20mg daily subcutaneous dose was well tolerated. (AAN Meeting ,SF 1996)

  • Avonex (interferon beta - 1a)
    This is a treatment for relapsing forms of multiple sclerosis.  It is administered intramuscular (into the muscle) one a week. Common side effects are mild flu like symptoms. Its advantage is lack of skin reactions.
  • Betaseron (interferon beta - 1b)
    This is a drug used to prevent relapses of multiple sclerosis. It is injected every other day. Common side effects are mild flu like symptoms.

  • Rebif (interferon beta - 1a)
    This is also a multiple sclerosis modifying drug that is given as an injection 3 times per week. It is similar to Avonex, but its advantage is a higher, more frequent dose of interferon.

  • Novantrone (mitoxantrone)
    This drug is reserved for advancing multiple scerosis not responding to the interferons or Copaxone. It is useful for progressive-relapsing or secondary-progressive forms of MS. It is given every 3 months or 4 times per year.

  • Tysabri (natalizumab)
    This is a prophylactic drug for multiple sclerosis relapses when the above treatments fail. It is rarely complicated by the develpment of PMA, a life threatening condition.

Migraine Drugs

  • Imitrex, Relpax, Maxalt, Frova, Zomig, and other triptans
    These drugs are part of the triptan family. They are useful in aborting migraine headaches.

  • DHE-45
    This drug has been around since 1945 and is very helpful for intractable migraine given intravenously.

  • Topamax, Depakote and Inderal (a beta blocker)
    The first two are seizure medications but are very useful as prophylatic drugs to prevent migraines that are more frequent than once a week. Each have their own side effect profile. Inderal is primarily a cardiac drug effective for migraine as well.